AS-19


SMILES CN([C@H]1CCc2c(C1)cccc2c1c(C)nn(c1C)C)C
InChIKey BTTOYOKCLDAHHO-HNNXBMFYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 283.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 9.22 9.22 9.22 Guide to Pharmacology
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 7.01 7.06 7.12 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 7.99 7.99 7.99 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.92 8.91 9.22 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.19 6.19 6.19 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.62 6.58 7.05 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 8.26 8.26 8.26 ChEMBL
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.51 6.51 6.51 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 6.97 6.97 6.97 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database