ARC-239


SMILES COc1ccccc1N1CCN(CC1)CCC1C(=O)c2ccccc2C(C1=O)(C)C
InChIKey OSEADGVOKYGIER-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 406.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Human Adrenoceptors A pKi 5.5 6.15 6.8 Guide to Pharmacology
α2B ADA2B Human Adrenoceptors A pKi 6.8 7.25 7.7 Guide to Pharmacology
α2C ADA2C Human Adrenoceptors A pKi 6.9 7.2 7.5 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database