UTP


SMILES O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O
InChIKey PGAVKCOVUIYSFO-XVFCMESISA-N

Chemical properties

Hydrogen bond acceptors 12
Hydrogen bond donors 7
Rotatable bonds 8
Molecular weight (Da) 484.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Endogenous
Approved drug Yes

Database connections

Structure pdb 9K0K

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 5.06 5.06 5.06 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.42 5.42 5.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
P2Y2 P2RY2 Human P2Y A pEC50 8.1 8.1 8.1 Guide to Pharmacology
P2Y4 P2RY4 Human P2Y A pEC50 6.3 6.3 6.3 Guide to Pharmacology
P2Y6 P2RY6 Human P2Y A pEC50 5.2 5.2 5.2 Guide to Pharmacology
P2Y11 P2Y11 Human P2Y A pEC50 5.2 5.2 5.2 Guide to Pharmacology
P2Y4 P2RY4 Rat P2Y A pEC50 5.6 5.6 5.6 Guide to Pharmacology
P2Y2 P2RY2 Rat P2Y A pEC50 6.89 6.89 6.89 ChEMBL
P2Y4 P2RY4 Rat P2Y A pEC50 5.58 5.58 5.58 ChEMBL
P2Y2 P2RY2 Mouse P2Y A pIC50 5.82 5.82 5.82 ChEMBL
P2Y2 P2RY2 Mouse P2Y A pEC50 5.9 5.9 5.9 ChEMBL
P2Y4 P2RY4 Human P2Y A pEC50 5.6 6.76 7.41 ChEMBL
P2Y6 P2RY6 Human P2Y A pEC50 5.22 5.6 6.37 ChEMBL
P2Y2 P2RY2 Human P2Y A pEC50 4.69 6.93 8.25 ChEMBL
P2Y2 P2RY2 Human P2Y A pEC50 8.09 8.09 8.09 Drug Central
P2Y4 P2RY4 Human P2Y A pEC50 8.2 8.2 8.2 Drug Central
P2Y6 P2RY6 Human P2Y A pEC50 8.28 8.28 8.28 Drug Central
P2Y11 P2Y11 Human P2Y A pEC50 8.28 8.28 8.28 Drug Central
P2Y4 P2RY4 Rat P2Y A pEC50 8.25 8.25 8.25 Drug Central