TUG-424


SMILES OC(=O)CCc1ccc(cc1)C#Cc1ccccc1C
InChIKey FODHWOBAQBTTFS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 264.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FFA1 FFAR1 Human Free fatty acid A pKi 6.2 6.2 6.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FFA1 FFAR1 Human Free fatty acid A pEC50 7.5 7.5 7.5 Guide to Pharmacology
FPR3 FPR3 Human Formylpeptide A pIC50 5.84 5.84 5.84 ChEMBL
GPR183 GP183 Human Orphan A pIC50 6.24 6.24 6.24 ChEMBL
FFA4 FFAR4 Human Free fatty acid A pEC50 5.65 5.75 5.84 ChEMBL
FFA1 FFAR1 Human Free fatty acid A pEC50 7.17 7.36 7.5 ChEMBL
S1P1 S1PR1 Human Lysophospholipid (S1P) A pIC50 6.6 6.6 6.6 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pIC50 6.22 6.22 6.22 ChEMBL
apelin APJ Human Apelin A pIC50 6.49 6.49 6.49 ChEMBL
FPR1 FPR1 Human Formylpeptide A pIC50 5.89 5.89 5.89 ChEMBL