TRV026


SMILES CC(C)[C@@H](C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)N[C@@H](CC3=CN=CN3)C(=O)N4CCC[C@H]4C(=O)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC
InChIKey MJQQGUJPWJCFMO-PITCCTKHSA-N
Sequence GRVYYHP

Chemical properties

Hydrogen bond acceptors 12
Hydrogen bond donors 12
Rotatable bonds 24
Molecular weight (Da) 903.5

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Structure pdb 6OS2

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
AT1 AGTR1 Human Angiotensin A pKi 8.29 8.29 8.29 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
AT1 AGTRA Rat Angiotensin A pEC50 7.42 7.42 7.42 ChEMBL
AT1 AGTR1 Human Angiotensin A pEC50 7.12 7.12 7.12 ChEMBL