triptorelin


SMILES OC[C@@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCC(=O)N)CCCNC(=N)N)CC(C)C)Cc1c[nH]c2c1cccc2)Cc1ccc(cc1)O)NC(=O)[C@H](Cc1c[nH]c2c1cccc2)NC(=O)[C@@H](NC(=O)[C@@H]1CCC(=O)N1)Cc1nc[nH]c1
InChIKey VXKHXGOKWPXYNA-PGBVPBMZSA-N
Sequence XHWSYWLRPG

Chemical properties

Hydrogen bond acceptors 15
Hydrogen bond donors 18
Rotatable bonds 33
Molecular weight (Da) 1310.6

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GnRH1 GNRHR Human Gonadotrophin-releasing hormone A pKi 9.29 9.39 9.49 Guide to Pharmacology
GnRH1 GNRHR Rat Gonadotrophin-releasing hormone A pKi 8.5 8.65 8.8 Guide to Pharmacology
GnRH1 GNRHR Rat Gonadotrophin-releasing hormone A pKi 8.06 8.06 8.06 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GnRH1 GNRHR Human Gonadotrophin-releasing hormone A pEC50 8.04 8.04 8.04 Drug Central