[3H]raclopride


SMILES CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(c1OC)Cl
InChIKey WAOQONBSWFLFPE-VIFPVBQESA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 346.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKd 8.9 8.9 8.9 Guide to Pharmacology
D1 DRD1 Pig Dopamine A pKi 4.43 4.43 4.43 ChEMBL
D3 DRD3 Rat Dopamine A pKi 8.03 8.03 8.03 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.48 8.51 8.96 ChEMBL
D2 DRD2 Rat Dopamine A pKd 8.15 8.68 8.96 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.51 5.51 5.51 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.82 8.0 8.43 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.51 8.0 8.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pIC50 7.5 7.92 8.89 ChEMBL
D2 DRD2 Human Dopamine A pIC50 6.98 7.87 8.74 ChEMBL