[3H]PAF


SMILES CCCCCCCCCCCCCCCCOC[C@@H](OC(=O)C)COP(=O)(OCC[N+](C)(C)C)[O-]
InChIKey HVAUUPRFYPCOCA-AREMUKBSSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 25
Molecular weight (Da) 523.4

Drug properties

Molecular type Lipid
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAF PTAFR Human Platelet-activating factor A pKd 8.8 8.85 8.9 Guide to Pharmacology
PAF PTAFR Human Platelet-activating factor A pKi 9.82 9.82 9.82 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.07 5.07 5.07 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 5.35 5.35 5.35 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 5.69 5.69 5.69 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.51 5.51 5.51 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.75 5.75 5.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAF PTAFR Human Platelet-activating factor A pIC50 9.55 9.55 9.55 ChEMBL