[3H]MK-912


SMILES O=C1N(C)[C@]2(CCN3[C@H](C2)c2oc4c(c2CC3)cccc4)CCN1C([3H])([3H])[3H]
InChIKey JRDUBBHIPPPSLP-NFEZXYISSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 1
Molecular weight (Da) 345.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Human Adrenoceptors A pKd 8.9 8.9 8.9 Guide to Pharmacology
α2B ADA2B Human Adrenoceptors A pKd 8.9 8.9 8.9 Guide to Pharmacology
α2C ADA2C Human Adrenoceptors A pKd 10.1 10.1 10.1 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database