[3H]GR 125,743


SMILES COc1ccc(cc1N1CCN(CC1)C([3H])([3H])[3H])NC(=O)c1ccc(c(c1)C)c1ccncc1
InChIKey GNOXPYACARZYMW-BHTRQJOGSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 422.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKd 8.6 8.9 9.2 Guide to Pharmacology
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKd 8.6 8.6 8.6 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database