[3H]AVP (human, mouse, rat)


SMILES NC(=O)CC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(N)=O
InChIKey MIFHTMACYGHZKT-LGYYRGKSSA-N
Sequence CYFQNCPRG

Chemical properties

Hydrogen bond acceptors 16
Hydrogen bond donors 16
Rotatable bonds 31
Molecular weight (Da) 1085.5

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
V1A V1AR Human Vasopressin and oxytocin A pKd 8.6 9.4 10.2 Guide to Pharmacology
V1B V1BR Human Vasopressin and oxytocin A pKd 8.6 9.1 9.6 Guide to Pharmacology
V2 V2R Human Vasopressin and oxytocin A pKd 8.4 8.9 9.4 Guide to Pharmacology
OT OXYR Human Vasopressin and oxytocin A pKd 8.8 8.85 8.9 Guide to Pharmacology
V2 V2R Rat Vasopressin and oxytocin A pKd 8.8 8.8 8.8 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database