[125I][Tyr26]galanin (pig)


SMILES CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)O
InChIKey WVFODTWUOPGPAP-CIJSCKBQSA-N
Sequence GWTLNSAGYLLGPHAIDNHRSFHDKYGLA

Chemical properties

Hydrogen bond acceptors 44
Hydrogen bond donors 45
Rotatable bonds 99
Molecular weight (Da) 3209.6

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GAL1 GALR1 Human Galanin A pKd 9.82 9.82 9.82 Guide to Pharmacology
GAL2 GALR2 Human Galanin A pKd 9.715 9.71 9.71 Guide to Pharmacology
GAL3 GALR3 Human Galanin A pKd 8.65 8.65 8.65 Guide to Pharmacology
GAL3 GALR3 Rat Galanin A pKd 9.01 9.13 9.26 Guide to Pharmacology
GAL2 GALR2 Rat Galanin A pKd 8.4 9.14 9.89 Guide to Pharmacology
GAL1 GALR1 Rat Galanin A pKd 9.52 10.12 10.72 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database