[125I][Tyr26]galanin (human)


SMILES NCCCC[C@@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CO)[C@H](O)C)CC(C)C)Cc1ccc(cc1)O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(=O)N)NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(cc1)O)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]([C@H](O)C)NC(=O)[C@H](Cc1c[nH]c2c1cccc2)NC(=O)CN)CC(C)C)CC(=O)N)CO)C)CC(C)C)CC(C)C)Cc1nc[nH]c1)C)Cc1nc[nH]c1)CCCN=C(N)N)CO)Cc1ccccc1)CO)CC(=O)O
InChIKey IBAFSRAMOWXNLI-CRUSWPMPSA-N
Sequence GWTLNSAGYLLGPHAVGNHRSFSDKYGLTS

Chemical properties

Hydrogen bond acceptors 46
Hydrogen bond donors 47
Rotatable bonds 99
Molecular weight (Da) 3204.6

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GAL1 GALR1 Human Galanin A pKd 9.07 9.07 9.07 Guide to Pharmacology
GAL2 GALR2 Human Galanin A pKd 9.51 9.57 9.62 Guide to Pharmacology
GAL2 GALR2 Rat Galanin A pKd 9.23 9.23 9.23 Guide to Pharmacology
GAL2 GALR2 Mouse Galanin A pKd 9.33 9.33 9.33 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database