[125I]ICYP


SMILES OC(COc1cccc2c1c([125I])c([nH]2)C#N)CNC(C)C
InChIKey WGSPBWSPJOBKNT-RFLHHMENSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 6
Molecular weight (Da) 397.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Human Adrenoceptors A pKd 10.4 10.85 11.3 Guide to Pharmacology
β2 ADRB2 Human Adrenoceptors A pKd 11.1 11.25 11.4 Guide to Pharmacology
β3 ADRB3 Human Adrenoceptors A pKd 9.2 9.5 9.8 Guide to Pharmacology
β3 ADRB3 Mouse Adrenoceptors A pKd 9.3 9.35 9.4 Guide to Pharmacology
β3 ADRB3 Rat Adrenoceptors A pKd 9.2 9.2 9.2 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database