[125I]HEAT (BE2254)


SMILES O=C1C(CNCCc2ccc(c(c2)[125I])O)CCc2c1cccc2
InChIKey DUOOAUBZMQZYLO-STTHPYEQSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 419.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pKd 9.7 9.8 9.9 Guide to Pharmacology
α1B ADA1B Human Adrenoceptors A pKd 9.9 10.05 10.2 Guide to Pharmacology
α1D ADA1D Human Adrenoceptors A pKd 9.5 9.7 9.9 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database