SR59230A


SMILES CCc1ccccc1OC[C@H](CN[C@H]1CCCc2c1cccc2)O
InChIKey VFDHMSXXELYMRW-ICSRJNTNSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 325.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Human Adrenoceptors A pKi 7.5 7.95 8.4 Guide to Pharmacology
β2 ADRB2 Human Adrenoceptors A pKi 8.5 8.9 9.3 Guide to Pharmacology
β3 ADRB3 Human Adrenoceptors A pKi 7.5 7.95 8.4 Guide to Pharmacology
β3 ADRB3 Human Adrenoceptors A pKd 7.16 7.16 7.16 ChEMBL
β1 ADRB1 Human Adrenoceptors A pKd 7.43 7.43 7.43 ChEMBL
β2 ADRB2 Human Adrenoceptors A pKd 8.42 8.42 8.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β3 ADRB3 Human Adrenoceptors A pEC50 6.72 6.72 6.72 ChEMBL
β1 ADRB1 Human Adrenoceptors A pEC50 7.32 7.32 7.32 ChEMBL
β2 ADRB2 Human Adrenoceptors A pEC50 8.06 8.06 8.06 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 4.4 4.4 4.4 ChEMBL