RX821002


SMILES COC1(COc2c(O1)cccc2)C1=NCCN1
InChIKey HQGWKNGAKBPTBX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 234.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Ligand site mutations α2A α2B

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Human Adrenoceptors A pKi 8.1 8.75 9.4 Guide to Pharmacology
α2B ADA2B Human Adrenoceptors A pKi 7.5 8.1 8.7 Guide to Pharmacology
α2C ADA2C Human Adrenoceptors A pKi 8.1 8.45 8.8 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database