PYY-(13-36) (mouse, rat, pig)


SMILES CC(C)C[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)[C@@H](C)O)C(C)C
InChIKey IAZLNMARDOOODL-PRZASUQOSA-N
Sequence SPEELSRYYASLRHYLNLVTRQRY

Chemical properties

Hydrogen bond acceptors 42
Hydrogen bond donors 45
Rotatable bonds 96
Molecular weight (Da) 3013.6

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Y2 NPY2R Human Neuropeptide Y A pKi 8.8 9.1 9.4 Guide to Pharmacology
Y5 NPY5R Human Neuropeptide Y A pKi 7.1 7.1 7.1 Guide to Pharmacology
Y1 NPY1R Rat Neuropeptide Y A pKi 7.5 7.5 7.5 Guide to Pharmacology
Y4 NPY4R Rat Neuropeptide Y A pKi 6.85 6.85 6.85 Guide to Pharmacology
Y5 NPY5R Rat Neuropeptide Y A pKi 7.1 7.1 7.1 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database