(+)-ADTN


SMILES NC1CCc2c(C1)cc(c(c2)O)O
InChIKey ASXGAOFCKGHGMF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 0
Molecular weight (Da) 179.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Ligand site mutations D2 D5

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 5.3 5.85 6.4 Guide to Pharmacology
D5 DRD5 Human Dopamine A pKi 6.0 6.0 6.0 Guide to Pharmacology
D2 DRD2 Rat Dopamine A pKi 7.18 7.18 7.18 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pIC50 6.16 6.16 6.16 ChEMBL