NPY-(3-36) (pig)


SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)[C@@H](C)O)[C@@H](C)CC
InChIKey CDGOTJUJFRUDRO-QJAFYHIKSA-N
Sequence SKPDNPGEDAPAEDLARYYSALRHYINLITRQRY

Chemical properties

Hydrogen bond acceptors 56
Hydrogen bond donors 57
Rotatable bonds 126
Molecular weight (Da) 3992.0

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Y2 NPY2R Human Neuropeptide Y A pKi 9.2 9.2 9.2 Guide to Pharmacology
Y5 NPY5R Human Neuropeptide Y A pKi 8.0 8.0 8.0 Guide to Pharmacology
Y1 NPY1R Rat Neuropeptide Y A pKi 7.7 7.7 7.7 Guide to Pharmacology
Y4 NPY4R Rat Neuropeptide Y A pKi 7.7 7.7 7.7 Guide to Pharmacology
Y5 NPY5R Rat Neuropeptide Y A pKi 8.7 8.7 8.7 Guide to Pharmacology
Y2 Q9ERC0 Rat Neuropeptide Y A pKi 9.1 9.1 9.1 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database