noradrenaline


SMILES NCC(c1ccc(c(c1)O)O)O
InChIKey SFLSHLFXELFNJZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 2
Molecular weight (Da) 169.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Endogenous
Approved drug No

Database connections

Ligand site mutations β1 β2

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Human Adrenoceptors A pKi 6.0 6.0 6.0 Guide to Pharmacology
β2 ADRB2 Human Adrenoceptors A pKi 5.4 5.4 5.4 Guide to Pharmacology
D1 DRD1 Human Dopamine A pKi 4.3 4.3 4.3 Guide to Pharmacology
D5 DRD5 Human Dopamine A pKi 4.9 4.9 4.9 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TA1 TAAR1 Human Trace amine A pEC50 4.91 4.91 4.91 ChEMBL