ARFORMOTEROL


SMILES COc1ccc(C[C@@H](C)NC[C@H](O)c2ccc(O)c(NC=O)c2)cc1
InChIKey BPZSYCZIITTYBL-YJYMSZOUSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 9
Molecular weight (Da) 344.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Structure pdb 7BZ2 6IBL 8JJ8 6TKO

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Human Adrenoceptors A pKd 8.16 8.16 8.16 Drug Central
β2 ADRB2 Human Adrenoceptors A pKd 8.07 8.07 8.07 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β2 ADRB2 Guinea pig Adrenoceptors A pEC50 9.5 9.8 9.9 ChEMBL
β3 ADRB3 Human Adrenoceptors A pEC50 7.6 7.6 7.6 ChEMBL
β1 ADRB1 Human Adrenoceptors A pEC50 6.96 7.29 7.4 ChEMBL
β2 ADRB2 Human Adrenoceptors A pEC50 8.58 9.2 9.5 ChEMBL
β3 ADRB3 Human Adrenoceptors A pEC50 8.12 8.12 8.12 Drug Central
β2 ADRB2 Guinea pig Adrenoceptors A pEC50 8.0 8.0 8.0 Drug Central