Ac-RYYRIK-NH2


SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCN=C(N)N)NC(C)=O)C(=O)N[C@@H](CCCCN)C(N)=O
InChIKey WBBBVZGQADABSU-RERZDIOCSA-N
Sequence RYYRIK

Chemical properties

Hydrogen bond acceptors 12
Hydrogen bond donors 14
Rotatable bonds 30
Molecular weight (Da) 938.5

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.82 8.96 9.1 Guide to Pharmacology
NOP OPRX Mouse Opioid A pKi 8.8 8.8 8.8 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 5.1 5.1 5.1 Guide to Pharmacology
NOP OPRX Human Opioid A pIC50 8.98 9.07 9.12 ChEMBL
NOP OPRX Human Opioid A pEC50 7.89 7.89 7.89 ChEMBL