ML290


SMILES CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C
InChIKey RSYHJSDOGMSLDH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 506.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.01 6.01 6.01 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
RXFP1 RXFP1 Human Relaxin family peptide A pEC50 7.03 7.03 7.03 Guide to Pharmacology
GPR183 GP183 Human Orphan A pIC50 5.44 5.44 5.44 ChEMBL
RXFP1 RXFP1 Human Relaxin family peptide A pEC50 4.77 6.45 10.37 ChEMBL
apelin APJ Human Apelin A pIC50 5.59 5.59 5.59 ChEMBL