(+)-aceclidine
| SMILES | CC(=O)O[C@@H]1C[NH+]2CCC1CC2 |
| InChIKey | WRJPSSPFHGNBMG-SECBINFHSA-O |
Chemical properties
| Hydrogen bond acceptors | 2 |
| Hydrogen bond donors | 1 |
| Rotatable bonds | 1 |
| Molecular weight (Da) | 170.1 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| M2 | ACM2 | Human | Acetylcholine (muscarinic) | A | pKi | 6.21 | 6.21 | 6.21 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| M1 | ACM1 | Human | Acetylcholine (muscarinic) | A | pEC50 | 5.4 | 5.4 | 5.4 | Guide to Pharmacology |
| M2 | ACM2 | Human | Acetylcholine (muscarinic) | A | pEC50 | 6.2 | 6.3 | 6.4 | Guide to Pharmacology |
| M3 | ACM3 | Human | Acetylcholine (muscarinic) | A | pEC50 | 5.7 | 5.7 | 5.7 | Guide to Pharmacology |
| M4 | ACM4 | Human | Acetylcholine (muscarinic) | A | pEC50 | 5.4 | 5.4 | 5.4 | Guide to Pharmacology |
| M5 | ACM5 | Human | Acetylcholine (muscarinic) | A | pEC50 | 5.5 | 5.5 | 5.5 | Guide to Pharmacology |