mesoridazine


SMILES CN1CCCCC1CCN1c2ccccc2Sc2c1cc(cc2)S(=O)C
InChIKey SLVMESMUVMCQIY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 386.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.98 6.98 6.98 Guide to Pharmacology
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.26 7.26 7.26 Guide to Pharmacology
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.39 6.39 6.39 Guide to Pharmacology
D1 DRD1 Human Dopamine A pKi 6.99 6.99 6.99 Guide to Pharmacology
D3 DRD3 Human Dopamine A pKi 7.64 7.64 7.64 Guide to Pharmacology
H1 HRH1 Human Histamine A pKi 8.06 8.06 8.06 Drug Central
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.19 8.19 8.19 Drug Central
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 8.15 8.15 8.15 Drug Central
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.11 8.11 8.11 Drug Central
D3 DRD3 Human Dopamine A pKi 8.07 8.07 8.07 Drug Central
D4 DRD4 Human Dopamine A pKi 8.09 8.09 8.09 Drug Central
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.16 8.16 8.16 Drug Central
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.09 8.09 8.09 Drug Central
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.17 8.17 8.17 Drug Central
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.1 8.1 8.1 Drug Central
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 8.11 8.11 8.11 Drug Central
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 8.14 8.14 8.14 Drug Central
D1 DRD1 Human Dopamine A pKi 8.16 8.16 8.16 Drug Central
D2 DRD2 Human Dopamine A pKi 8.11 8.11 8.11 Drug Central
D2 DRD2 Human Dopamine A pKi 8.66 8.66 8.66 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database