Enprostil


SMILES COC(=O)CCC=C=CC[C@H]1[C@H](\C=C\[C@H](O)COC2=CC=CC=C2)[C@@H](O)CC1=O
InChIKey PTOJVMZPWPAXER-FPXSIRDUSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 10
Molecular weight (Da) 400.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP4 PE2R4 Human Prostanoid A pKi 8.13 8.13 8.13 Drug Central
FP PF2R Human Prostanoid A pKi 8.15 8.15 8.15 Drug Central
EP3 PE2R3 Rat Prostanoid A pKi 8.15 8.15 8.15 Drug Central
EP1 PE2R1 Rat Prostanoid A pKi 8.17 8.17 8.17 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP1 PE2R1 Human Prostanoid A pEC50 8.12 8.12 8.12 Drug Central
EP3 PE2R3 Human Prostanoid A pEC50 8.1 8.1 8.1 Drug Central