Beraprost


SMILES [H][C@]12C[C@@H](O)[C@H](\C=C\[C@@H](O)C(C)CC#CC)[C@@]1([H])C1=C(O2)C(CCCC(O)=O)=CC=C1
InChIKey CTPOHARTNNSRSR-APJZLKAGSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 8
Molecular weight (Da) 398.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP3 PE2R3 Human Prostanoid A pKi 8.21 8.21 8.21 Drug Central
EP4 PE2R4 Human Prostanoid A pKi 8.29 8.29 8.29 Drug Central
IP PI2R Rat Prostanoid A pKi 8.11 8.11 8.11 Drug Central
IP PI2R Mouse Prostanoid A pKi 8.11 8.11 8.11 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
IP PI2R Human Prostanoid A pIC50 8.08 8.08 8.08 Drug Central