AC264613


SMILES Brc1cccc(c1)/C(=N/NC(=O)[C@@H]1C(=O)NC[C@H]1c1ccccc1)/C
InChIKey RQKXQCSEZPQBNZ-QSBCOWLBSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 399.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.41 5.41 5.41 ChEMBL
H1 HRH1 Human Histamine A pKi 5.7 5.7 5.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAR2 PAR2 Human Proteinase-activated A pEC50 7.5 7.5 7.5 Guide to Pharmacology
PAR2 PAR2 Human Proteinase-activated A pEC50 7.5 7.51 7.52 ChEMBL