CHEMBL407213


SMILES CC(=O)N[C@H]1CC(=O)NCCCC[C@H](C(N)=O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC1=O
InChIKey OQIKSFAMWBMLCU-NVCPMKERSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 10
Rotatable bonds 10
Molecular weight (Da) 823.4

Drug properties

Molecular type Protein
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Human Melanocortin A pKi 6.14 6.14 6.14 ChEMBL
MC3 MC3R Human Melanocortin A pKi 6.72 6.72 6.72 ChEMBL
MC4 MC4R Human Melanocortin A pKi 8.37 8.37 8.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Human Melanocortin A pEC50 6.0 6.0 6.0 ChEMBL