ANGIOTENSIN-II


SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O
InChIKey CUKWUWBLQQDQAC-VEQWQPCFSA-N

Chemical properties

Hydrogen bond acceptors 13
Hydrogen bond donors 14
Rotatable bonds 27
Molecular weight (Da) 969.5

Drug properties

Molecular type Protein
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
AT2 AGTR2 Human Angiotensin A pKi 9.96 9.96 9.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
AT1 AGTRA Rat Angiotensin A pEC50 7.82 7.98 8.14 ChEMBL
AT2 AGTR2 Human Angiotensin A pIC50 9.68 9.68 9.68 ChEMBL
AT1 AGTR1 Human Angiotensin A pEC50 7.68 7.68 7.68 ChEMBL