CHEMBL105462


SMILES C[C@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O
InChIKey WZHKXNSOCOQYQX-FUAFALNISA-N
Sequence None

Chemical properties

Hydrogen bond acceptors 9
Hydrogen bond donors 11
Rotatable bonds 23
Molecular weight (Da) 872.4

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ghrelin GHSR Human Ghrelin A pKi 8.22 8.22 8.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ghrelin GHSR Rat Ghrelin A pEC50 8.0 8.38 8.77 ChEMBL
ghrelin GHSR Human Ghrelin A pIC50 5.22 7.29 8.44 ChEMBL