CHEMBL5076846


SMILES C[C@H]1C[C@H](NS(=O)(=O)c2cc3ccc(F)cc3s2)CN1CCCc1noc2cc(F)ccc12
InChIKey UHSHPGFICACACL-KSSFIOAISA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 491.1

Drug properties

Molecular type Unknown
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.31 7.31 7.31 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.05 7.05 7.05 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.19 9.19 9.19 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.27 7.27 7.27 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database