lotiglipron


SMILES C[C@@]1(OC2=CC=CC(=C2O1)C3CCN(CC3)CC4=NC5=C(N4C[C@@H]6CCO6)C=C(C=C5)C(=O)O)C7=NC=C(C=C7)Cl
InChIKey SVPYZAJTWFQTSM-UGDMGKLASA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 574.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GLP-1 GLP1R Human Glucagon B1 pEC50 9.02 9.02 9.02 Guide to Pharmacology
GLP-1 GLP1R Human Glucagon B1 pEC50 8.04 8.04 8.04 ChEMBL