CHEMBL4798829


SMILES c1ccc2oc(-c3csc(C4CCN(Cc5nc6ncccc6[nH]5)CC4)n3)cc2c1
InChIKey JOCPQSJABURDDD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 415.1

Drug properties

Molecular type Unknown
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pKi 5.46 5.46 5.46 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.28 5.28 5.28 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.25 6.25 6.26 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 5.26 5.31 5.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database