TP-030-2


SMILES CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21
InChIKey KHVVJKLNKLQLJZ-SFHVURJKSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 480.1

Drug properties

Molecular type Unknown
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 5.54 5.54 5.55 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 5.53 5.54 5.55 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 5.63 5.63 5.63 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.68 5.68 5.69 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database