BAY-309


SMILES Cc1cc(NC(=O)c2cccc(S(F)(F)(F)(F)F)c2)cc(-n2ccn3nc(-c4cccnc4)cc23)c1
InChIKey MOONEVNPHKFNGV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 519.1

Drug properties

Molecular type Unknown
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.67 5.67 5.67 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.31 5.31 5.31 ChEMBL
δ OPRD Human Opioid A pKi 5.76 5.76 5.76 ChEMBL
κ OPRK Human Opioid A pKi 5.0 5.0 5.0 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.0 5.0 5.0 ChEMBL
μ OPRM Human Opioid A pKi 5.16 5.16 5.16 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database