BAY-897


SMILES O=C(Nc1ccc(Oc2ccc(F)cc2)cc1)N1CCc2ncccc2[C@H]1c1ccc(F)cc1
InChIKey AEOSDPHCSPJLGL-AREMUKBSSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 457.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.28 5.28 5.28 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.96 5.96 5.97 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.43 5.43 5.43 ChEMBL
κ OPRK Human Opioid A pKi 5.5 5.5 5.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database