AMILORIDE
| SMILES | N=C(N)NC(=O)c1nc(Cl)c(N)nc1N |
| InChIKey | XSDQTOBWRPYKKA-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 6 |
| Hydrogen bond donors | 5 |
| Rotatable bonds | 1 |
| Molecular weight (Da) | 229.0 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | Yes |
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| A2A | AA2AR | Human | Adenosine | A | pKi | 4.92 | 5.11 | 5.48 | ChEMBL |
| A2A | AA2AR | Human | Adenosine | A | pKi | 8.26 | 8.26 | 8.26 | Drug Central |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| TSH | TSHR | Human | Glycoprotein hormone | A | Potency | 4.4 | 4.4 | 4.4 | ChEMBL |