METHYLPHENIDATE


SMILES COC(=O)C(c1ccccc1)C1CCCCN1
InChIKey DUGOZIWVEXMGBE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 233.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Human Adrenoceptors A pKi 8.28 8.28 8.28 Drug Central
α2B ADA2B Human Adrenoceptors A pKi 8.25 8.25 8.25 Drug Central
α2C ADA2C Human Adrenoceptors A pKi 8.22 8.22 8.22 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TSH TSHR Human Glycoprotein hormone A Potency 4.5 4.5 4.5 ChEMBL