CHEMBL6199292


SMILES NCCOCCOCCC(=O)NCCOCCOCCNc1ccccc1C(=O)N1CCC(N2CCC(Cc3ccc(S(=O)(=O)c4cccc(Cl)c4)cc3)CC2)CC1
InChIKey IGRKWQHZZFAVJG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 11
Hydrogen bond donors 3
Rotatable bonds 24
Molecular weight (Da) 841.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 8.07 8.07 8.07 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.21 8.21 8.21 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.43 6.43 6.43 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 8.96 8.96 8.96 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.95 6.95 6.95 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M2 ACM2 Human Acetylcholine (muscarinic) A pIC50 6.97 6.97 6.97 ChEMBL