CHEMBL6198855


SMILES NCCOCCOCCNc1ccccc1C(=O)N1CCC(N2CCC(Cc3ccc(S(=O)(=O)c4cccc(Cl)c4)cc3)CC2)CC1
InChIKey PADQFXUBJOYKEO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 15
Molecular weight (Da) 682.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 8.07 8.07 8.07 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.13 8.13 8.13 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.3 6.3 6.3 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 8.82 8.82 8.82 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.84 6.84 6.84 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M2 ACM2 Human Acetylcholine (muscarinic) A pIC50 6.88 6.88 6.88 ChEMBL