CHEMBL6189985


SMILES CCC1CN2CCNCc3ccc(C(=O)NCC(F)F)c1c32
InChIKey GJNVOHZANYBSHY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 309.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 4.92 4.92 4.92 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.55 7.65 7.75 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 4.62 5.37 6.12 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.96 8.03 8.1 ChEMBL