CHEMBL6189522


SMILES CCCNC(=O)c1ccc2c3c1C(CC(F)(F)F)CN3CCNC2
InChIKey DIUAEPSKDJOMHF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 341.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.65 6.65 6.65 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.28 7.38 7.48 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.14 5.9 6.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.64 7.64 7.65 ChEMBL