CHEMBL6189062


SMILES O=C(NCC(F)(F)F)c1ccc2c3c1C(CC(F)(F)F)CN3CCNC2
InChIKey XWRNJTHEONWDQX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 381.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.29 5.29 5.29 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.04 7.04 7.04 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.13 5.13 5.13 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 6.75 6.75 6.75 ChEMBL