CHEMBL6189046


SMILES CNC(=O)c1ccc2c3c1C(CC(F)(F)F)CN3CCNC2
InChIKey KTHWMUSORLGHET-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 313.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 4.75 5.06 5.37 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.0 6.71 7.72 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.3 5.6 5.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.03 7.49 7.94 ChEMBL