CHEMBL6149486


SMILES CCOc1ccc(CCN2C(=N)N(CCN(CCN3C[C@H]([C@@H](C)O)N(CCc4ccc(C)cc4)C3=N)CCN3C(=N)NC[C@@H]3C)C[C@@H]2CCCNC(=N)N)cc1
InChIKey ZKOKPMBVSPCKTF-BRQNREJHSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 8
Rotatable bonds 22
Molecular weight (Da) 773.6

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Mouse Melanocortin A pKd 5.7 5.7 5.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Mouse Melanocortin A pEC50 6.22 6.22 6.22 ChEMBL
MC1 MSHR Mouse Melanocortin A pEC50 5.92 5.92 5.92 ChEMBL
MC4 MC4R Mouse Melanocortin A pEC50 5.26 5.26 5.26 ChEMBL