CHEMBL6101825


SMILES Clc1ccc2c(c1)CC1(Cc3nnc(N4CCN(c5cccc6c5OCC6)CC4)n3-2)OCCO1
InChIKey JXPQCMGVIQVMKK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 479.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
V1A V1AR Mouse Vasopressin and oxytocin A pKi 9.3 9.3 9.3 ChEMBL
V2 V2R Human Vasopressin and oxytocin A pKi 9.28 9.28 9.28 ChEMBL
V1A V1AR Human Vasopressin and oxytocin A pKi 9.89 9.89 9.89 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
V1A V1AR Human Vasopressin and oxytocin A pIC50 8.66 8.66 8.66 ChEMBL