CHEMBL6070230


SMILES O=C(c1ccccc1)N(c1ccccc1)C1CCN(CCc2ccccc2)CC1
InChIKey BJPDWVPQDSVQKD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 384.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.96 6.96 6.96 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.92 6.92 6.92 ChEMBL
δ OPRD Human Opioid A pKi 5.29 5.29 5.29 ChEMBL
κ OPRK Human Opioid A pKi 5.3 5.3 5.3 ChEMBL
μ OPRM Human Opioid A pKi 7.86 8.15 8.45 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Mouse Opioid A pIC50 4.69 5.04 5.39 ChEMBL
α1A ADA1A Human Adrenoceptors A pIC50 5.32 5.32 5.32 ChEMBL
μ OPRM Human Opioid A pEC50 7.53 7.89 8.25 ChEMBL