CHEMBL6062608


SMILES Cc1cc(OCCCN2CCC(c3noc4cc(F)ccc34)CC2)cc2c1CCN(C)C2=O
InChIKey XLBCSWQHJMLCPP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 451.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 8.17 8.17 8.17 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.06 8.06 8.06 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.55 8.55 8.55 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database